We are an interdisciplinary research group focusing on droplets and soft granular matter physics, and tissue engineering. We use droplet microfluidics to formulate and study droplet-based materials as well as to engineer biomaterials at the microscale for new applications in 3D cell culture and tissue engineering.
Soft granular materials are structures composed of close-packed deformable particles, droplets, or other types of ‘grains’. Examples include compressed emulsions, foams, or dense micro-hydrogel suspensions, widespread in food, cosmetic, and pharmaceutical industries. We focus on developing new strategies of formulation of such ‘wet’ granular materials with high precision using microfluidics. We use viscous flows to generate and manipulate droplets inside microchannels and build larger granular structures exploiting capillary and viscous forces. We study mechanical properties and self-assembly of droplet aggregates, clusters, or threads. We also exploit microfluidics and 3D printing to engineer biomaterials, e.g., fabricate porous hydrogel scaffolds for cell seeding or formulate cell-laden hydrogel microstructures as microparticles/microfibers as building blocks of larger tissue-like constructs. The great promise of the living tissue-like microstructures is their application in:
We are offering a Student/Master Student position at the First TEAM project: “New Applications of Droplet Microfluidics: From Biomimetics To…
Tissue engineering is an interdisciplinary field aiming at the fabrication of living tissues and organs in vitro. In the group, we focus on the new strategies of formulation of biomaterials.
3D printing is an additive biofabrication strategy based on the deposition of the printed biomaterial layer by layer. Among multiple challenges associated with this emerging technology, we focus on the printing of microfluidic emulsions foams or suspensions.
Droplet microfluidics is a set of techniques associated with the generation and manipulation of droplets ‘on-chip’, typically inside microchannels. In the group, we cover high throughput droplet generation, formulation of multiple emulsions, and generation of hydrogel microbeads from microdroplet templates.
Soft granular matter refers to materials composed of close-packed deformable microscopic ‘grains’. In the group, we develop new microfluidic strategies of formulation of such structures while also exploring their application as cell scaffolds for tissue engineering.